Detalhe da pesquisa
1.
Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice.
Cell
; 185(4): 641-653.e17, 2022 02 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35123651
2.
HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes.
Nature
; 623(7989): 1026-1033, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37993716
3.
Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.
Immunity
; 51(5): 915-929.e7, 2019 11 19.
Artigo
Inglês
| MEDLINE | ID: mdl-31732167
4.
Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers.
Immunity
; 40(5): 657-68, 2014 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24768347
5.
Membrane Env Liposomes Facilitate Immunization with Multivalent Full-Length HIV Spikes.
J Virol
; 95(13): e0000521, 2021 06 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33883221
6.
Functional Optimization of Broadly Neutralizing HIV-1 Antibody 10E8 by Promotion of Membrane Interactions.
J Virol
; 92(8)2018 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29386285
7.
Functional Stability of HIV-1 Envelope Trimer Affects Accessibility to Broadly Neutralizing Antibodies at Its Apex.
J Virol
; 91(24)2017 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28978711
8.
Covalent Linkage of HIV-1 Trimers to Synthetic Liposomes Elicits Improved B Cell and Antibody Responses.
J Virol
; 91(16)2017 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28592540
9.
Dense Array of Spikes on HIV-1 Virion Particles.
J Virol
; 91(14)2017 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28446665
10.
Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.
J Virol
; 89(13): 6725-45, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25878116
11.
Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization.
PLoS Pathog
; 10(7): e1004271, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25058619
12.
Trimerization of the HIV Transmembrane Domain in Lipid Bilayers Modulates Broadly Neutralizing Antibody Binding.
Angew Chem Int Ed Engl
; 55(8): 2688-92, 2016 Feb 18.
Artigo
Inglês
| MEDLINE | ID: mdl-26799917
13.
Increased functional stability and homogeneity of viral envelope spikes through directed evolution.
PLoS Pathog
; 9(2): e1003184, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23468626
14.
Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10.
J Immunol
; 191(6): 3186-3191, 2013 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23940276
15.
Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature
; 445(7129): 732-7, 2007 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17301785
16.
Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions.
Proc Natl Acad Sci U S A
; 107(4): 1529-34, 2010 Jan 26.
Artigo
Inglês
| MEDLINE | ID: mdl-20080706
17.
A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin.
Mol Ther Methods Clin Dev
; 28: 366-384, 2023 Mar 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36879849
18.
A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals.
PLoS Pathog
; 6(8): e1001028, 2010 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-20700449
19.
Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface.
Proc Natl Acad Sci U S A
; 106(22): 9057-62, 2009 Jun 02.
Artigo
Inglês
| MEDLINE | ID: mdl-19458040
20.
In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1.
J Virol
; 84(7): 3382-95, 2010 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-20089658